Protective effect of cyclovirobuxine D derivatives on alcohol induced injury in PC12 cells
نویسندگان
چکیده
To explore the impact of the new derivatives cyclovirobuxine D (CBV-D) model of alcohol-induced injury in PC12 cells. The model of alcohol-induced injury in PC12 cells, new derivatives of the cyclovirobuxine D PC12 cells by MTT assay, Hoechst 33258 staining and lactate dehydrogenase (LDH) activity was measured. The new D derivatives cyclovirobuxine inhibit the damage caused by alcohol PC12 cells, apoptosis rate, while LDH release was reducing. cyclovirobuxine D derivatives on PC12 cell damage caused by excitatory amino acids have a protective effect.
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